1. Van Ewijk H, Bralten J ..., Franke B (2017). Female-specific association of NOS1 genotype with white matter microstructure in ADHD patients and controls. Journal of Child Psychology and Psychiatry 58:8 (2017), pp 958–966. doi:10.1111/jcpp.12742. Epub 2017 Jun 7.

    https://www.ncbi.nlm.nih.gov/pubmed/28219628
  2. Hoogman M, ..., Franke B (2017). Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis. Lancet Psychiatry. 2017 Apr;4(4):310-319. doi: 10.1016/S2215-0366(17)30049-4. Epub 2017 Feb 16.

    https://www.ncbi.nlm.nih.gov/pubmed/28219628
  3. Klein M, Onnink M, van Donkelaar M, Wolfers T, Harich B, Shi Y, Dammers J, Arias-Vásquez A, Hoogman M, Franke B (2017). Brain imaging genetics in ADHD and beyond − mapping pathways from gene to disorder at different levels of complexity. Neurosci Biobehav Rev. 2017 Jan 31.pii: S0149-7634(16)30478-X. doi: 10.1016/j.neubiorev.2017.01.013.

    http://www.sciencedirect.com/science/article/pii/S014976341630478X
  4. Martín-García E, Fernández-Castillo N, Burokas A, Gutiérrez-Cuesta J, Sánchez-Mora C, Casas M, Ribasés M, Cormand B, Maldonado R (2015). Frustrated expected reward induces differential transcriptional changes in the mouse brain. Addict Biol.. 2015 Jan; 20(1): 22-37. doi: 10.1111/adb. 12188. Epub2014 Oct 6.

    http://www.ncbi.nlm.nih.gov/pubmed/25288320
  5. Cline BH, Anthony DC, Lysko A, Dolgov O, Anokhin K, Schroeter C, Malin D, Kubatiev A, Steinbusch HW, Lesch KP, Strekalova T (2014). Lasting downregulation of the lipid peroxidation enzymes in the prefrontal cortex of mice susceptible to stress-induced anhedonia. Behavioural Brain Research, 2014 Apr 28. doi: 10.1016/j.bbr.2014.04.037. [Epub ahead of print].

    http://www.ncbi.nlm.nih.gov/pubmed/24786329
  6. Costa-Nunes J, Zubareva O, Araújo-Correia M, Valença A, Schroeter CA, Pawluski JL, Vignisse J, Steinbusch H, Hermes D, Phillipines M, Steinbusch HM, Strekalova T (2014). Altered emotionality, hippocampus-dependent performance and expression of NMDA receptor subunit mRNAs in chronically stressed mice. Stress, 2014 Jan 17(1):108-16. doi: 10.3109/10253890.2013.872619.

    http://www.ncbi.nlm.nih.gov/pubmed/24308441
  7. Jones LI, Norton WH (2014). Using zebrafish to uncover the genetic and neural basis of aggression, a frequent comorbid symptom of psychiatric disorders. Behavioural Brain Research, 2014 Jun 2. doi: 10.1016/j.bbr.2014.05.055. [Epub ahead of print]

    http://www.ncbi.nlm.nih.gov/pubmed/24954772
  8. Kiser DP, Rivero O, Lesch KP (2014). The genetics of neurodevelopmental disorders in the era of whole-genome sequencing: Unveiling the dark matter. J Child Psychol Psychiatry, in press.
  9. Laas K, Reif A, Akkermann K, Kiive E, Lesch KP, Veidebaum T, Harro J (2014). Neuropeptide S receptor gene variant and environment: contribution to alcohol use disorders and alcohol consumption. Addiction Biology, 2014 Apr 23. doi: 10.1111/adb.12149. [Epub ahead of print]

    http://www.ncbi.nlm.nih.gov/pubmed/24754478
  10. Lesch KP (2014). Editorial: Illuminating the dark matter of developmental neuropsychiatric genetics - strategic focus for future research in child psychology and psychiatry. Journal of Child Psychology and Psychiatry, 2014 March, 55(3):201-203. doi: 10.1111/jcpp.12223.

    http://www.ncbi.nlm.nih.gov/pubmed/24552481
  11. Pomytkin IA, Cline BH, Anthony DC, Steinbusch HW, Lesch KP, Strekalova T (2014). Endotoxaemia resulting from decreased serotonin tranporter (5-HTT) function: A reciprocal risk factor for depression and insulin resistance? Behavioural Brain Research, 2014 May 9. doi: 10.1016/j.bbr.2014.04.049. [Epub ahead of print]

    http://www.ncbi.nlm.nih.gov/pubmed/24815315
  12. Schraut KG, Jakob SB, Weidner MT, Schmitt AG, Scholz CJ, Strekalova T, El Hajj N, Eijssen LMT, Domschke K, Reif A, Haaf T, Ortega G, Steinbusch HWM, Lesch KP, Van den Hove DL. Prenatal stress-induced programming of genome-wide promoter DNA  methylation in 5-HTT deficient mice. Translational Psychiatry, 2014 Oct 21. doi: doi: 10.1038/tp.2014.107.

    http://www.ncbi.nlm.nih.gov/pubmed/25335169
  13. Schwarz R, Reif A, Scholz CJ, Weissflog L, Schmidt B, Lesch KP, Jacob C, Reichert S, Heupel J, Volkert J, Kopf J, Hilscher M, Weber H, Kittel-Schneider S (2014). A preliminary study on methylphenidate-regulated gene expression in lymphoblastoid cells of ADHD patients.The World Journal of Biological Psychiatry, 2014 Aug 27:1-10. [Epub ahead of print]

    http://www.ncbi.nlm.nih.gov/pubmed/25162476
  14. Strekalova T, Evans M, Chernopiatko A, Couch Y, Costa-Nunes J, Cespuglio R, Chesson L, Vignisse J, Steinbusch HW, Anthony DC, Pomytkin I, Lesch KP (2014). Deuterium content of water increases depression susceptibility: The potential role of a serotonin-related mechanism. Behavioural Brain Research, 2015 Jan 15. doi: 10.1016/j.bbr.2014.07.039. [Epub 2014 Aug 1].

    http://www.ncbi.nlm.nih.gov/pubmed/25092571
  15. Vaht M, Merenäkk L, Mäestu J, Veidebaum T, Harro J (2014). Serotonin transporter gene promoter polymorphism (5-HTTLPR) and alcohol use in general population: interaction effect with birth cohort. Psychopharmacology (Berl), 2014 Jul; 231(13):2587-94. doi: 10.1007/s00213-013-3427-8.

    http://www.ncbi.nlm.nih.gov/pubmed/24408213
  16. Veroude K, Zhang-James Y, Fernàndez-Castillo N, Bakker MJ, Cormand B, Faraone SV (2015). Genetics of aggressive behaviour: An overview.. Am J Med Genet B Neuropsychiatr Genet., 2015 Sept 8. doi: 10.1002/ajmg.b.32364.

    http://www.ncbi.nlm.nih.gov/pubmed/26345359
  17. Aebi M, van Donkelaar MM, Poelmans G, Buitelaar JK, Sonuga-Barke EJ, Stringaris A; IMAGE consortium, Faraone SV, Franke B, Steinhausen HC, van Hulzen KJ (2015). Gene-set and multivariate genome-wide association analysis of oppositional defiant behavior subtypes in attention-deficit/hyperactivity disorder.. Am J Med Genet B Neuropsychiatr Genet., 2015 Jul 16. doi: 10.1002/ajmg.b.32346.

    http://www.ncbi.nlm.nih.gov/pubmed/26184070
  18. Freudenberg F, Carreño Gutierrez H, Post AM, Reif A, Norton WH. (2015). Aggression in non-human vertebrates: Genetic mechanisms and molecular pathways.. Am J Med Genet B Neuropsychiatr Genet., 2015 Aug 19. doi: 10.1002/ajmg.b.32358.

    http://www.ncbi.nlm.nih.gov/pubmed/26284957
  19. Zhang-James Y, Faraone SV. (2015). Genetic architecture for human aggression: A study of gene-phenotype relationship in OMIM.. Am J Med Genet B Neuropsychiatr Genet., 2015 Aug 19. doi: 10.1002/ajmg.b.32363.

    http://www.ncbi.nlm.nih.gov/pubmed/26288127
  20. Fernàndez-Castillo N, Cormand B. (2015). Aggressive behavior in humans: genes and pathways ientified through association studies.. Am J Med Genet B Neuropsychiatr Genet., 2015 Jul. doi: 10.1002/ajmg.b.32419.

    http://www.ncbi.nlm.nih.gov/pubmed/26773414
  21. Brevik et al. (2016). Genome-Wide Analyses of Aggressiveness in Attention-Deficit Hyperactivity Disorders.. Am J Med Genet B Neuropsychiatr Genet., 2016 Jul. doi: 10.1002/ajmg.b.32434.

    http://www.ncbi.nlm.nih.gov/pubmed/27021288
  22. Fernàndez-Castillo et al. (2015). Transcriptomic and genetic studies identify NFAT5 as a candidate gene for cocaine dependence. Translational Psychiatry., 2015 doi: 10.1038/tp.2015.158.

    https://www.ncbi.nlm.nih.gov/pubmed/26506053
  23. Asherson et al. (2016). The genetics of aggression: Where are we now?. Am J Med Genet B Neuropsychiatr Genet., 2016 doi: 10.1002/ajmg.b.32450.

    https://www.ncbi.nlm.nih.gov/pubmed/27061441
  24. Zayats et al. (2016). Exome chip analyses in adult attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet., 2016 doi: 10.1038/tp.2016.196.

    https://www.ncbi.nlm.nih.gov/pubmed/27754487
  25. Holz et al. (2016). Ventral striatum and amygdala activity serve as convergence sites for childhood adversity and conduct disorder. Soc Cogn Affect Neurosci, 2016., doi: 10.1093/scan/nsw120

    https://www.ncbi.nlm.nih.gov/pubmed/27694318
  26. Holz et al. (2016). Gene x environment interactions in conduct disorder: Implications for future treatments. Neurosci Biobehav Rev, 2016., doi: 10.1016/j.neubiorev.2016.08.017

    https://www.ncbi.nlm.nih.gov/pubmed/27545756
  27. Grünwald et al. (2016). Functional Impact of An ADHD-Associated DIRAS2 Promoter Polymorphism. Neuropsychopharmacology, 2016., doi: 10.1038/npp.2016.113

    https://www.ncbi.nlm.nih.gov/pubmed/27364329
  28. van Hulzen et al. (2016). Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis. Biological Psychiatry, 2016 doi: 10.1016/j.biopsych.2016.08.040

    https://www.ncbi.nlm.nih.gov/pubmed/27890468
  29. Mooney et al. (2016). Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2016 doi: 10.1002/ajmg.b.32446

    https://https://www.ncbi.nlm.nih.gov/pubmed/27004716
  30. Freitag et al. (2016). The role of ASTN2 variants in childhood and adult ADHD, comorbid disorders and associated personality traits. Journal of Neural Transmission, 2016 doi: 10.1007/s00702-016-1553-2.

    https://www.ncbi.nlm.nih.gov/pubmed/27138430
  31. Kittel-Schneider et al. (2016). DGKH genetic risk variant influences gene expression in bipolar affective disorder. Journal of Affective Disorders, 2016 doi: 10.1016/j.jad.2016.03.041.

    https://www.ncbi.nlm.nih.gov/pubmed/27016658
  32. Kittel-Schneider et al. (2016). Cytogenetic Effects of Chronic Methylphenidate Treatment and Chronic Social Stress in Adults with Attention-Deficit/Hyperactivity Disorder. Pharmacopsychiatry., 2016 doi: 10.1055/s-0035-1569361.

    https://www.ncbi.nlm.nih.gov/pubmed/26926233
  33. Kittel-Schneider et al. (2015). Multi-level biomarker analysis of nitric oxide synthase isoforms in bipolar disorder and adult ADHD. Journal of Psychopharmacology., 2015 doi: 10.1177/0269881114555251.

    https://www.ncbi.nlm.nih.gov/pubmed/25320160
  34. Candemir et al. (2016). Interaction of NOS1AP with the NOS-I PDZ domain: Implications for schizophrenia-related alterations in dendritic morphology. European Neuropsychopharmacology., 2016 doi: 10.1016/j.euroneuro.2016.01.008.

    https://www.ncbi.nlm.nih.gov/pubmed/26861996
  35. Freudenberg et al. (2014). Neuronal nitric oxide synthase (NOS1) and its adaptor, NOS1AP, as a genetic risk factors for psychiatric disorders. Genes, Brain and Behaviour., 2014 doi: 10.1111/gbb.12193.

    https://www.ncbi.nlm.nih.gov/pubmed/25612209
  36. Freudenberg et al. (2015). The role of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in depression: central mediators of pathophysiology and antidepressant activity?. Neuroscience and Biobehavioural Reviews., 2015 doi: 10.1016/j.neubiorev.2015.03.005.

    https://www.ncbi.nlm.nih.gov/pubmed/25783220
  37. Sánchez-Mora et al. (2015). Dopamine receptor DRD4 gene and stressful life events in persistent attention deficit hypeeractivity disorder. American Journal of Medical Genetics B Neuropsychiatric Genetics., 2015 doi: 10.1002/ajmg.b.32340.

    https://www.ncbi.nlm.nih.gov/pubmed/26174753
  38. Cabana-Dominguez et al. (2016). Transcriptomic and genetic studies identify NFAT5 as a candidate gene for cocaine dependence. Scientific Report., 2016 doi: 10.1038/srep31033.
  39. Toverud Landaas et al. (2016). Vitamin levels in adults with ADHD;. BJPsych Open., 2016 doi: 10.1192/bjpo.bp.116.003491.
  40. Freudenberg et al. (2016). Aggression in non-human vertebrates: Genetic mechanisms and molecular pathways. Am J Med Genet B Neuropsychiatr Genet., 2016 doi: 10.1002/ajmg.b.32358.

    https://www.ncbi.nlm.nih.gov/pubmed/26284957
  41. Lehto et al. (2014). Effect of tryptophan hydroxylase-2 gene polymorphism G-703 T on personality in a population representative sample. Prog Neuropsychopharmacol Biol Psychiatry, 2014 doi: 10.1016/j.pnpbp.2014.10.005.

    https://www.ncbi.nlm.nih.gov/pubmed/25455586
  42. Lehto et al. (2016). BDNF Val66Met genotype and neuroticism predict life stress: A longitudinal study from childhood to adulthood. European Neuropsychopharmacology, 2016 doi: 10.1016/j.euroneuro.2015.12.029.

    https://www.ncbi.nlm.nih.gov/pubmed/26738427
  43. Laas et al. (2015). Further evidence for the association of the NPSR1 gene A/T polymorphism (Asn107Ile) with impulsivity and hyperactivity. Journal of Psychopharmacology, 2015 doi: 10.1177/0269881115573803.

    https://www.ncbi.nlm.nih.gov/pubmed/25744621
  44. Kiive et al. (2014). The interaction effect of the tryptophan hydroxylase-2 G-703T genotype and stressful life events on inattentive and hyperactive behaviour in adolescents. World Congress of Psychiatric Genetics, 2014
  45. Vaht et al. (2016). A functional vesicular monoamine transporter 1 (VMAT1) gene variant is associated with affect and the prevalence of anxiety, affective and alcohol use disorders in a longitudinal population-representative birth cohort study. International Journal of Neuropsychopharmacology , 2016 doi: 10.1093/ijnp/pyw013.

    https://www.ncbi.nlm.nih.gov/pubmed/26861143
  46. Vaht et al. (2016). Oxytocin receptor gene variation rs53576 and alcohol abuse in a longitudinal population representative study. Psychoneuroendocrinology, 2016 doi: 10.1016/j.psyneuen.2016.09.018.

    https://www.ncbi.nlm.nih.gov/pubmed/27716573
  47. Vaht et al. (2016). A functional neuregulin-1 gene variant and stressful life events: Effect on drug use in a longitudinal population-representative cohort study. Journal of Psychopharmacology , 2016 doi: 10.1177/0269881116655979.

    https://www.ncbi.nlm.nih.gov/pubmed/27353026
  48. Harro et al. (2016). The role of MAO in personality and drug use. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 2016 doi: 10.1016/j.pnpbp.2016.02.013.

    https://www.ncbi.nlm.nih.gov/pubmed/26964906
  49. Tomson et al. (2016). Effect of a human serotonin 5-HT2A receptor gene polymorphism on impulsivity: Dependence on cholesterol levels. Journal of Affective Disorders, 2016 doi: 10.1016/j.jad.2016.07.036.

    https://www.ncbi.nlm.nih.gov/pubmed/27455355
  50. Domínguez et al. (2016). A Highly Polymorphic Copy Number Variant in the NSF Gene is Associated with Cocaine Dependence, 2016 doi: 10.1038/srep31033.

    https://www.ncbi.nlm.nih.gov/pubmed/27498889
  51. Klein et al. (2016). Meta-analysis of the DRD5 VNTR in persistent ADHD, 2016 doi: 10.1016/j.euroneuro.2016.06.012.

    https://www.ncbi.nlm.nih.gov/pubmed/27480019
  52. Noordermeer et al. (2015). Neurocognitive Deficits in Attention-Deficit/Hyperactivity Disorder With and Without Comorbid Oppositional Defiant Disorder, 2015 doi: 10.1177/1087054715606216.
  53. Mostert J.C. et al. (2015). Similar Subgroups Based on Cognitive Performance Parse Heterogeneity in Adults With ADHD and Healthy Controls, 2015 doi: 10.1177/1087054715602332.
  54. Biedermann J. et al. (2005). Attention-deficit hyperactivity disorder, 2015 doi: 10.1016/S0140-6736(05)66915-2.
  55. Klein et al. (2015). Converging evidence does not support GIT1 as an ADHD risk gene, 2015 doi: 10.1002/ajmg.b.32327.

    http://onlinelibrary.wiley.com/doi/10.1002/ajmg.b.32327/abstract
  56. Vrijsen J et al. (2015). Interaction of the 5-HTTLPR and childhood trauma influences memory bias in healthy individuals, 2015 doi: 10.1016/j.jad.2015.06.008.

    https://www.ncbi.nlm.nih.gov/pubmed/26232751
  57. Rivero O et al. (2015). Cadherin-13, a risk gene for ADHD and comorbid disorders, impacts GABAergic function in hippocampus and cognition, 2015 doi: 10.1038/tp.2015.152.

    http://www.nature.com/tp/journal/v5/n10/full/tp2015152a.html
  58. Drgonova J et al. (2016). Cadherin 13: Human cis-Regulation and Selectively Altered Addiction Phenotypes and Cerebral Cortical Dopamine in Knockout Mice, 2016 doi: 10.2119/molmed.2015.00170.

    https://www.ncbi.nlm.nih.gov/pubmed/27579475
  59. Kiser D et al. (2015). Annual Research Review: The (epi)genetics of neurodevelopmental disorders in the era of whole-genome sequencing - unveiling the dark matter, 2015 doi: 10.1111/jcpp.12392.

    https://www.ncbi.nlm.nih.gov/pubmed/25677560
  60. Markova N et al. (2015). Thiamine and benfotiamine improve cognition and ameliorate GSK-3β-associated stress-induced behaviours in mice, 2015 doi: 10.1016/j.pnpbp.2016.11.001.

    https://www.ncbi.nlm.nih.gov/pubmed/27825907
  61. Strekalova T et al. (2016). Individual Differences in Behavioural Despair Predict Brain GSK-3beta Expression in Mice: The Power of a Modified Swim Test, 2016 doi: 10.1155/2016/5098591.

    https://www.hindawi.com/journals/np/2016/5098591/
  62. Couch Y et al. (2016). Low-dose lipopolysaccharide (LPS) inhibits aggressive and augments depressive behaviours in a chronic mild stress model in mice, 2016 doi: 10.1186/s12974-016-0572-0.

    https://www.ncbi.nlm.nih.gov/pubmed/27184538
  63. Morozova A. et al. (2016). Ultrasound of alternating frequencies and variable emotional impact evokes depressive syndrome in mice and rats, 2016 doi: 10.1016/j.pnpbp.2016.03.003.

    https://www.ncbi.nlm.nih.gov/pubmed/27036099
  64. Strekalova T. et al. (2016). Insulin receptor sensitizer, dicholine succinate, prevents both Toll-like receptor 4 (TLR4) upregulation and affective changes induced by a high-cholesterol diet in mice, 2016 doi: 10.1016/j.jad.2016.02.045.

    https://www.ncbi.nlm.nih.gov/pubmed/26921863
  65. Buitelaar N. J. L. et al. (2015). ADHD in Childhood and/or Adulthood as a Risk Factor for Domestic Violence or Intimate Partner Violence: A Systematic Review, 2015 doi: 10.1177/1087054715587099.

    http://journals.sagepub.com/doi/pdf/10.1177/1087054715587099
  66. Herpers P.C.M. et al. (2016). Associations between high callous–unemotional traits and quality of life across youths with non-conduct disorder diagnoses, 2016 doi: 10.1007/s00787-015-0766-5.

    https://www.ncbi.nlm.nih.gov/pubmed/26362863
  67. Smeets K.C. et al. (2016). Are Proactive and Reactive Aggression Meaningful Distinctions in Adolescents? A Variable- and Person-Based Approach, 2016 doi: 10.1007/s10802-016-0149-5.

    https://www.ncbi.nlm.nih.gov/labs/articles/27113216/
  68. Brugman S. et al. (2016). Examining the reactive proactive questionnaire in adults in forensic and non-forensic settings: A variable- and person-based approach, 2016 doi: 10.1002/ab.21671.
  69. Blair R.J.R. et al. (2016). Neuro-cognitive system dysfunction and symptom sets: A review of fMRI studies in youth with conduct problems, 2016 doi: 10.1016/j.neubiorev.2016.10.022.
  70. Veroude K.V. et al. (2016). The link between callous-unemotional traits and neural mechanisms of reward processing: An fMRI study, 2016 doi: 10.1016/j.pscychresns.2016.08.005.

    https://www.ncbi.nlm.nih.gov/pubmed/27564545
  71. Persico A.M. et al. (2015). Unmet needs in paediatric psychopharmacology: Present scenario and future perspectives, 2015 doi: 10.1016/j.euroneuro.2015.06.009.

    https://www.ncbi.nlm.nih.gov/pubmed/26166453